Use a grid pattern for your photos with the twist of having white borders.
Grids are so wonderful for making quick layouts with lots of photos. I was scrambling to finish my nephew's first year album, so having a grid made it so easy! I just arranged all the photos into the grid design in Photoshop, leaving a bit of white in between the photos, and printed them off. Then I just place the whole sheet on the layout and bingo bappo, done!